Nanoporous glass is a universal matrix in which, by impregnating various substances, it is possible to initiate the appearance of properties uncharacteristic of glass. In this case, the porosity of glass can be controlled by heat treatment, creating a material with a given structure and properties. In this work, we studied the effect of heat treatment on the structure of porous glass impregnated with gold, and revealed the potential of this material as active substrates for Raman spectroscopy.