The issues of the possibility of using composite ceramics based on biogenic hydroxyapatite (BHA) as carriers of cultured stem cells are considered. The results of studies of the microstructure and biochemical activity of glass-ceramic samples based on BHA with a maximum fraction of open porosity, prepared for use as substrates for cloning fibroblast cells in vitro, are presented. The results of a visual assessment using fluorescence microscopy of cell adhesion and their proliferative activity on bioresorbable membrane-type substrates made of a composite material based on biogenic hydroxyapatite are also presented. Tab. 2, ill. 4, bibliography: 8 titles.
Dr. Phys.-Math. Sci. L. A. Ivanchenko
1 (
This email address is being protected from spambots. You need JavaScript enabled to view it. ), A. R. Parkhomey
1 , Dr. med. sciences A.G. Popandopulo
2 , A. V. Oberemko
2 ;
1 Institute for Problems of Materials Science. I. N. Frantsevich National Academy of Sciences of Ukraine (Ukraine, Kiev),
2 State Institution "V.K. Gusak Institute of Emergency and Reconstructive Surgery of the Academy of Medical Sciences of Ukraine" (Ukraine, Donetsk)
Kasten P., Luginb & uuml; hlR., Van Griensven et al. Comparison of human bone marrow stromalcells seeded on calcium-deficient hydroxyapatite, ? -tricalcium phosphate and demineralized bone matrix // Biomaterials. 2003. V. 24. P. 2593 - 2603.
Klimovitsky V. G., Grin V. K., Vasilenko I. V. et al. Inductive properties of carriers of mesenchymal stem cells // Trauma. 2007. T. 8. No. 3. S.
243-247 . Knabe C., Berger G., Gilderhaar R. et al. The functional expression of human bone-derived cells grown on rapidly resorbable calcium phosphate ceramics // Biomaterials. 2004. V. 25. P. 335 - 344.
DL Mastryukova, BI Beletskiy, OV Polukhina. Glass ceramics with an adjustable pore structure for medicine // Glass and ceramics. 2007. N 4. S. 23 - 26. Mastryukova DL, Beletskii BI, Polukhina OV Glass ceramics with controllable pore structure for medicine // Glass and Ceram. 2007. V. 64. N 3 - 4. P. 132 - 135.
Sulima V. S, Panchenko LM Immunological preparation of mobility of materials on the basis of biological hydroxyapatite for the prevention of cystic defects // Galitskiy Likarskiy Vichy. 2002. T. 9.N. 1.S. 87 - 89.
Pat. on corisne model N 37194. Vugletsny biomaterial / O. R. Parkhomey, L. A. Ivanchenko, R. V. Luchko, N. D. Pinchuk; publ. 11/25/2008 // Bul. 2008. No. 22.
Sych O., Pinchuk N., Parkhomey A. et al. Morphology and properties of new porous biocomposites based on biogenic hydroxyapatite and synthetic calcium phosphates // Functional Materials. 2007. V. 14. N 4. P. 430 - 435.
Haberko K., Bu & # 269; ko M., Brzezi & # 328; ska-Miecznik Ja et al. Natural hydroxyapatite - its behavior during heat treatment // Journal of Europian Ceramics Society. 2006. V. 26. P. 537 - 542.
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