Steklo i Keramika (Glass and Ceramics). Monthly scientific, technical and industrial journal

 

ISSN 0131-9582 (Online)

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Glass and glass ceramics containing oxides of heavy metals (Bi, Ta, W) in amount of 40 wt. % were obtained for use in medicine as radiosensitizers. The properties of the composites were studied in vitro: generation of secondary radiation, chemical solubility, change in pH of the medium during resorption. Indicators of secondary radiation and the pH value of the environment decrease in the order: W>Ta>Bi. Solubility indices decrease in the order: W > Bi > Ta. Despite the maximum generation of secondary ionizing radiation, W-containing ceramics based on Bioglass 45S5 are undesirable for use in vivo due to rapid dissolution and high alkalization of the environment.
Dina N. Grishchenko – senior researcher, Candidate of Chemical Sciences, Institute of Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Vladivostok, Russia
Olga S. Plotnikova – assistant, Institute of Surgery, Pacific State Medical University of the Ministry of Health of the Russian Federation, Vladivostok, Russia
Valery G. Kuryavyi – senior researcher, Candidate of Chemical Sciences, Institute of Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Vladivostok, Russia
Vladimir I. Apanasevich – Doctor of Medical Sciences, Professor, Institute of Surgery, Pacific State Medical University of the Ministry of Health of the Russian Federation, Vladivostok, Russia
Michael A. Medkov – Doctor of Chemical Sciences, Professor, Institute of Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Vladivostok, Russia
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Grishchenko D. N., Plotnikova O. S., Kuryavyi V. G., Apanasevich V. I., Medkov M. A. Materials based on bioglass 45S5, doped with heavy elements, for use as radiosensitizers. Steklo i keramika. 2024:97(05):3-10. (in Russ). DOI: 10.14489/glc.2024.05.pp.003-010