Ceramics in the Ca2P2O7–Ca3(PO4)2 system were obtained from powder mixtures containing calcium hydroxyapatite Са10(РО4)6(ОН)2 of natural origin and monocalcium phosphate monohydrate Ca(H2PO4)2·H2O. Fish scale powder was used as a source of calcium hydroxyapatite Са10(РО4)6(ОН)2 of natural origin. The molar ratios of Са10(РО4)6(ОН)2/Ca(H2PO4)2·H2O in the initial powder mixture equal to 1/4, 3/5 and 2/1 ensured the formation ceramics with phase composition, including calcium pyrophosphate Ca2P2O7 and/or tricalcium phosphate Ca3(PO4)2 after firing.
The homogenization of the components was carried out using repeated passing of the powder mixture through a sieve with a cell size of 200 microns. Plastic molding of the samples was carried out using ethyl alcohol as a binder. According to XRD data the phase composition of all samples after the addition of alcohol, molding and drying included monocalcium phosphate monohydrate Ca(H2PO4)2·H2O and calcium hydroxyapatite Са10(РО4)6(ОН)2. In the phase composition of the samples monetite CaHPO4 and brushite CaHPO4·2H2O were also present. The phase composition of prepared highly porous ceramic samples with relative density 27…55 % after firing in the range of 900…1100 ?C included ?-tricalcium phosphate ?-Ca3(PO4)2 and/or ?-calcium pyrophosphate ?-Ca2P2O7.
Tatiana V. Safronova – PhD (Engineering), senior researcher, Department of Chemistry, Materials Science Department, Lomonosov Moscow State University, Moscow, Russia
Xinyan Х. Feng – student, Materials Science Department, Lomonosov Moscow State University, Moscow, Russia
Viktor I. Vorobyov – PhD (Engineering), Associate Professor of the Department of Chemistry, Institute of Agroengineering and Food Systems, Kaliningrad State Technical University, Moscow, Russia
Xiaoling Х. Liao – PhD, Professor, Chongqing Key Laboratory of Nanomaterials and Devices, Chongqing University of Science and Technology, Chongqing, China
Tatiana B. Shatalova – PhD (Chemistry), Associate Professor, Department of Chemistry, Materials Science Department, Lomonosov Moscow State University, Moscow, Russia
Yaroslav Yu. Filippov – PhD (Chemistry), senior researcher, Institute of Mechanics, Materials Science Department, Lomonosov Moscow State University, Moscow, Russia
Albina M. Murashko – student, Faculty of Materials Sciences, Lomonosov Moscow State University, Moscow, Russia
Tatiana V. Filippova – engineer, Department of Chemistry, Lomonosov Moscow State University, Moscow, Russia
Zichen Х. Xu – PhD (Biomedical engineering), Lecturer, Chongqing Key Laboratory of Nanomaterials and Devices, Chongqing University of Science and Technology (CQUST), Chongqing, China
Marat M. Akhmedov – student, The Kosygin State University of Russia, Moscow, Russia
Nataliya R. Kildeeva – Doctor of Sci. (Chemistry), Professor, The Kosygin State University of Russia, Moscow, Russia
1. Hou X., Zhang L., Zhou Z., et al. Calcium phosphate-based biomaterials for bone repair // Journal of Functional Biomaterials. 2022. V. 13, No. 4. 187. P. 1 – 39. URL: https://doi.org/10.3390/jfb13040187
2. Fiume E., Magnaterra G., Rahdar A., et al.Hydroxyapatite for biomedical applications: A short overview // Ceramics. 2021. V. 4, No. 4. P. 542 – 563. URL: https://doi.org/10.3390/ceramics4040039
3. Сафронова Т. В., Путляев В. И. Медицинское неорганическое материаловедение в России: кальцийфос-фатные материалы // Наносистемы: физика, химия, математика. 2013. Т. 4, № 1. С. 24 – 47. URL: https://elibrary.ru/item.asp?id=18964052
4. Aoki K., Ideta H., Komatsu Y., et al. Bone-regeneration therapy using biodegradable scaffolds: calcium phosphate bioceramics and biodegradable polymers // Bioengineering. 2024. V. 11, No. 2. 180. P. 1 – 20. URL: https://doi.org/10.3390/bioengineering11020180
5. Wu V. M., Uskokovi? V. Is there a relationship between solubility and resorbability of different calcium phosphate phases in vitro? // Biochimica et Biophysica Acta (BBA)-General Subjects. 2016. V. 1860(10). P. 2157 – 2168. URL: https://doi.org/10.1016/j.bbagen.2016.05.022
6. Солоненко А. П., Шевченко А. Е., Полонянкин Д. А. Исследование динамики резорбции в трисбуфере гранул на основе гидроксиапатита, волластонита и желатина // Неорганические материалы. 2023. Т. 59, № 3. С. 341 – 348. URL: https://doi.org/10.31857/S0002337X23030144
7. Путляев В. И., Сафронова Т. В. Новое поколение кальцийфосфатных биоматериалов: роль фазового и химического составов // Стекло и керамика. 2006. Т. 79, № 3. С. 30 – 33. URL: https://glass-ceramics.ru/ru/archivru/27-biomaterialy/2091-1046. [Putlyaev V. I., Safronova T. V. A new generation of calcium phosphate biomaterials: The role of phase and chemical compositions // Glass Ceram. 2006. V. 63. P. 99 – 102. URL: https://doi.org/10.1007/s10717-006-0049-1]
8. Сафронова Т. В. Неорганические материалы для регенеративной медицины // Неорганические материалы. 2021. Т. 57, № 5. С. 467 – 499. URL: http://dx.doi.org/10.31857/S0002337X21050067. [Safronova T. V. Inorganic materials for regenerative medicine // Inorganic Materials. 2021. V. 57, No. 5. P. 443 – 474. URL: http://dx.doi.org/10.1134/S002016852105006X]
9. Brown P. W. Phase relationships in the ternary system CaO–P2O5–H2O at 25 °C // J. Am. Ceram. Soc. 1992. V. 75, No. 1. P. 17 – 22. URL: https://doi.org/10.1111%2Fj.1151-2916.1992.tb05435.x
10. Safronova T. V., Putlyaev V. I. Powder systems for calcium phosphate ceramics // Inorganic Materials. 2017. V. 53. P. 17 – 26.
11. Сафронова Т. В., Путляев В. И., Иванов В. К. и др. Порошковые смеси на основе гидрофосфата аммония и карбоната кальция для получения биосовместимой пористой керамики в системе СаО–Р2О5 // Новые огнеупоры. 2015. Т. 1, № 9. С. 45 – 53. URL: https://newogneup.elpub.ru/jour/article/view/11/13. [Safronova T. V., Putlyaev V. I., Ivanov V. K., et al. (2016). Powders mixtures based on ammonium pyrophosphate and calcium carbonate for preparation of biocompatible porous ceramic in the CaO–P2O5 system // Refractories and Industrial Ceramics. 2016. V. 56. P. 502 – 509. URL: https://doi.org/10.1007/s11148-016-9877-x]
12. Hsu C. K. The preparation of biphasic porous calcium phosphate by the mixture of Ca(H2PO4)2·H2O and CaCO3 // Materials chemistry and physics. 2003. V. 80, No. 2. P. 409 – 420. URL: https://doi.org/10.1016/S0254-0584(02)00166-9
13. Тошев О. У., Сафронова Т. В., Миронова Ю. С. и др. Ультрапористая субмикронная керамика на основе ?-Ca3(PO4)2 // Неорганические материалы. 2022. Т. 58, № 11. С. 1249 – 1260. URL: http://dx.doi.org/10.31857/S0002337X22110148. [Toshev O. U., Safronova T. V., Mironova Yu. S., et al. Ultraporous submicron-grained ?-Ca3(PO4)2-based ceramics // Inorganic Materials. 2022. V. 58, No. 11. P. 1208 – 1219. URL: http://dx.doi.org/10.1134/S0020168522110140]
14. Сафронова Т. В., Корнейчук С. А., Шаталова Т. Б. и др. Керамика в системе Са2Р2О7–Са(РО3)2, полученная обжигом цементного камня на основе ?-трикальцийфосфата и монокальцийфосфата моногидрата // Стекло и керамика. 2020. Т. 93, № 5. С. 3 – 13. URL: https://elibrary.ru/item.asp?id=44705975. [Safronova T. V., Korneichuk S. A., Shatalova T. B., et al. Ca2P2O7–Ca(PO3)2 ceramic obtained by firing ?-tricalcium phosphate and monocalcium phosphate monohydrate based cement stone // Glass Ceram. 2020. V. 77. P. 165 – 172. URL: https://doi.org/10.1007/s10717-020-00263-y
15. Safronova T. V., Mukhin E. A., Putlyaev V. I., et al. Amorphous calcium phosphate powder synthesized from calcium acetate and polyphosphoric acid for bioceramics application // Ceramics International. 2017. V. 43. P. 1310 – 1317. URL: http://dx.doi.org/10.1016/j.ceramint.2016.10.085
16. Safronova T. V., Paianidi Y. A., Shatalova T. B., et al. Preparation of calcium polyphosphate powder containing amorphous carbon // J. Ind. Chem. Soc. 2020. V. 97, No. 10c. P. 2106 – 2110. URL: http://dx.doi.org/10.5281/zenodo.5666129
17. Сафронова Т. В., Киселев А. С., Шаталова Т. Б. и др. Синтез моногидрата двойного пирофосфата кальция/аммония Ca(NH4)2P2O7?H2O – предшественника биосовместимых фаз кальцийфосфатной керамики // Изв. АН. Сер. хим. 2020. № 1. С. 139. URL: https://elibrary.ru/item.asp?id=42303370. [Safronova T. V., Kiselev A. S., Shatalova T. B., et al. Synthesis of double ammonium/calcium pyrophosphate monohydrate Ca(NH4)2P2O7.H2O as the precursor of biocompatible phases of calcium phosphate ceramics // Russian Chemical Bulletin. 2020. V. 69, No. 1. P. 139 – 147. URL: https://doi.org/10.1007/s11172-020-2735-5]
18. Haider A., Haider S., Han S. S., Kang I. K. Recent advances in the synthesis, functionalization and biomedical applications of hydroxyapatite: a review // RSC Advances. 2017. V. 7, No. 13. Р. 7442 – 7458. URL: https://doi.org/10.1039/C6RA26124H
19. Szcze? A., Ho?ysz L., Chibowski E. Synthesis of hydroxyapatite for biomedical applications // Advances in colloid and interface science. 2017. V. 249. Р. 321 – 330. URL: https://doi.org/10.1016/j.cis.2017.04.007
20. Okpe P. C., Folorunso O., Aigbodion V. S., Obayi C. Hydroxyapatite synthesis and characterization from waste animal bones and natural sources for biomedical applications // Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2024. V. 112, No. 7. Р. e35440. URL: https://doi.org/10.1002/jbm.b.35440
21. Arokiasamy P., Abdullah M. M. A. B., Abd Rahim S. Z., et al. Synthesis methods of hydroxyapatite from natural sources: A review // Ceramics International. 2022. V. 48, No. 11. P. 14959 – 14979. URL: https://doi.org/10.1016/j.ceramint.2022.03.064
22. Pon-On W., Suntornsaratoon P., Charoenphandhu N., et al. Hydroxyapatite from fish scale for potential use as bone scaffold or regenerative material // Materials Science and Engineering: C. 2016. V. 62. P. 183 – 189. URL: https://doi.org/10.1016/j.msec.2016.01.051
23. Seikh Z., De B., Ghosh D., et al. An overview on the utilization of hydroxyapatite from fish wastes: a transition from waste to wealth // J. Inst. Eng. India Ser. D. 2024. URL: https://doi.org/10.1007/s40033-024-00778-6
24. Coppola D., Lauritano C., Palma Esposito F., et al. Fish waste: From problem to valuable resource // Mar. Drugs. 2021. V. 19. P. 116. URL: https://doi.org/10.3390/md19020116
25. Arvanitoyannis I. S., Kassaveti A. Fish industry waste: treatments, environmental impacts, current and potential uses // Int. J. Food Sci. Technol. 2008. V. 43, No. 4. Р. 726 – 745. URL: https://doi.org/10.1111/j.1365-2621.2006.01513.x
26. Granito R. N., Renno A. C. M., Yamamura H., et al. Hydroxyapatite from fish for bone tissue engineering: A promising approach // International journal of molecular and cellular medicine. 2018. V. 7, No. 2. P. 80. URL: https://doi.org/10.22088%2FIJMCM.BUMS.7.2.80
27. Zakaria K. A., Yatim N. I., Ali N. A., Rastegari H. Recycling phosphorus and calcium from aquaculture waste as a precursor for hydroxyapatite (HAp) production: a review // Environmental Science and Pollution Research. 2022. V. 29, No. 31. P. 46471 – 46486. URL: https://doi.org/10.1007/s11356-022-20521-6
28. Ibrahim M. A., Abdelmonem M., Ismail N., et al. Ceramic hydroxyapatite derived from fish scales in biomedical applications; a systematic review // Precis. Nanomed. 2024. V. 7, No. 2. P. 1297 – 1311. URL: https://doi.org/10.33218/001c.120415
29. Sych E. E., Pinchuk N. D., Tovstonog A. B., et al. The structure and properties of calcium phosphate ceramics produced from monetite and biogenic hydroxyapatite // Powder Metall. Met. Ceram. 2014. V. 53. Р. 423 – 430. URL: https://doi.org/10.1007/s11106-014-9634-y
30. Oktar F. N., Unal S., Gunduz O., et al. Marine-derived bioceramics for orthopedic, reconstructive and dental surgery applications // Journal of the Australian Ceramic Society. 2023. V. 59, No. 1. P. 57 – 81.
31. Gil-Duran S., Arola D., Ossa E. A. Effect of chemical composition and microstructure on the mechanical behavior of fish scales from Megalops Atlanticus // J. Mech. Behav. Biomed. Mater. 2016. V. 56. Р. 134 – 145. URL: https://doi.org/10.1016/j.jmbbm.2015.11.028
32. Sionkowska A., Kozlowska J. Fish scales as a biocomposite of collagen and calcium salts // Key Eng. Mater. 2013. V. 587. P. 185 – 190. URL: https://doi.org/10.4028/www.scientific.net/KEM.587.185
33. Caruso G., Floris R., Serangeli C., Di Paola L. Fishery wastes as a yet undiscovered treasure from the sea: Biomolecules sources, extraction methods and valorization // Mar. Drugs. 2020. V. 18. P. 622. URL: https://doi.org/10.3390/md18120622
34. Измайлов Р. Р., Голованова О. А. Растворимость гидроксилапатита и карбонатгидроксилапатита, полученных из модельного раствора синовиальной жидкости человека // Вестник Омского университета. 2012. № 4(66). С. 109 – 113. URL: https://elibrary.ru/item.asp?id=21004124
35. Фомин А. С., Комлев В. С., Баринов С. М. и др. Синтез нанопорошков гидроксиапатита для медицинских применений // Перспективные материалы. 2006. № 2. С. 51 – 55. URL: https://www.elibrary.ru/item.asp?id=12969193
36. Boskey A. L. Hydroxyapatite formation in a dynamic collagen gel system: effects of type I collagen, lipids, and proteoglycans // The Journal of Physical Chemistry. 1989. V. 93, No. 4. P. 1628 – 1633. URL: https://doi.org/10.1021/j100341a086
37. Safronova T., Vorobyov V., Kildeeva N., et al. Inorganic powders prepared from fish scales // Ceramics. 2022. V. 5. P. 484 – 498. URL: https://doi.org/10.3390/ceramics5030037
38. Воробьев В. И., Нижникова Е. В. Получение фрак-ций коллагена и гидроксиапатита из рыбьей чешуи // Извес-тия КГТУ. 2021. № 62. С. 80 – 91. URL: https://www.elibrary.ru/item.asp?id=46369968
39. Пат. РФ RU 2021 116 247. Способ обработки рыбьей чешуи для получения коллагена и гидроксиапатита / В. И. Во-робьев. Опубл. 03.06.2021. URL: https://new.fips.ru/registers-doc-view/fips_servlet?DB=RUPAT&DocNumber=2021116247&TypeFile=html
40. ICDD. International Centre for Diffraction Data; Kabekkodu S., Ed.; ICDD: Newtown Square, PA, USA, 2010; PDF-4+ 2010 (Database). URL: https://www.icdd.com/pdf-2/
The article can be purchased
electronic!
PDF format
700 руб
DOI: 10.14489/glc.2024.09.pp.028-042
Article type:
Research Article
Make a request
